RT Journal Article
T1 Influenza vaccine effectiveness assessment through sentinel virological data in three post-pandemic seasons
A1 Torner, Nuria
A1 Martínez, Ana
A1 Basile, Luca
A1 Marcos, M. Angeles
A1 Antón, Andrés
A1 Mosquera, M. Mar
A1 Isanta, Ricard
A1 Cabezas, Carmen
A1 Jané, Mireia
A1 Dominguez, Angela
A1 Aizpurua, P.
A1 Alonso, J.
A1 Azemar, J.
A1 Basas, D.
A1 Besora, R.
A1 Callado, M.
A1 Casanovas, J. M.
A1 Cid, A.
A1 Ciurana, E.
A1 Cots, J. M.
A1 De La Rica, D.
A1 Elizalde Del Rio, G.
A1 Estabanell, A.
A1 Fau, E.
A1 Fernandez, O.
A1 Ferrer, C.
A1 Forcada, A.
A1 Forga, F. X.
A1 Fos, E.
A1 Gadea, G.
A1 Garcia, J.
A1 Garrido, P.
A1 Gatius, C.
A1 Grivé, M.
A1 Guzman, M. C.
A1 Hernandez, R.
A1 Juscafresa, D.
A1 Leon, I.
A1 Macia, E.
A1 Mainou, A.
A1 Marco, E.
A1 Martinez, M.
A1 Martinez, E.
A1 Molinero, C.
A1 Moncosi, X.
A1 Lopez-Mompó, C.
A1 Naranjo, M. A.
A1 Navarro, D.
A1 Ortola, M. E.
A1 Pérez, M. C.
A1 Perez, M. M.
A1 Prat, M.
A1 Pujol, R.
A1 Pujol, J.
A1 Ribatallada, A.
A1 Sánchez, R.
A1 Sarra, N.
A1 Teixidor, A.
A1 Valen, E.
A1 Valencia, I.
A1 Van Esso, D.
A1 Vila, C.
A1 Zabala, E.
A1 Zurilla, E.
AB Influenza vaccination aims at reducing the incidence of serious disease, complications and death among those with the most risk of severe influenza disease. Influenza vaccine effectiveness (VE) through sentinel surveillance data from the PIDIRAC program (Daily Acute Respiratory Infection Surveillance of Catalonia) during 2010-2011, 2011-2012, and 2012-2013 influenza seasons, with three different predominant circulating influenza virus (IV) types [A(H1N1)pdm09, A(H3N2) and B, respectively] was assessed. The total number of sentinel samples with known vaccination background collected during the study period was 3173, 14.7% of which had received the corresponding seasonal influenza vaccine. 1117 samples (35.2%) were positive for IV. A retrospective negative case control design was used to assess vaccine effectiveness (VE) for the entire period and for each epidemic influenza season. An overall VE of 58.1% (95% CI:46.8-67) was obtained. Differences in VE according to epidemic season were observed, being highest for the 2012-2013 season with predominance of IV type B (69.7% ;95% CI:51.5-81) and for the 2010-2011 season, with predominance of the A(H1N1) pdm09 influenza virus strain (67.2% ;95%CI:49.5-78.8) and lowest for the 2011-2012 season with A(H3N2) subtype predominance (34.2% ;95%CI:4.5-54.6). Influenza vaccination prevents a substantial number of influenza-associated illnesses. Although vaccines with increased effectiveness are needed and the search for a universal vaccine that is not subject to genetic modifications might increase VE, nowadays only the efforts to increase vaccination rates of high-risk population and healthcare personnel let reduce the burden of influenza and its complications.
SN 2164-5515
YR 2015
FD 2015-01-01
LK https://hdl.handle.net/11556/4380
UL https://hdl.handle.net/11556/4380
LA eng
NO Torner , N , Martínez , A , Basile , L , Marcos , M A , Antón , A , Mosquera , M M , Isanta , R , Cabezas , C , Jané , M , Dominguez , A , Aizpurua , P , Alonso , J , Azemar , J , Basas , D , Besora , R , Callado , M , Casanovas , J M , Cid , A , Ciurana , E , Cots , J M , De La Rica , D , Elizalde Del Rio , G , Estabanell , A , Fau , E , Fernandez , O , Ferrer , C , Forcada , A , Forga , F X , Fos , E , Gadea , G , Garcia , J , Garrido , P , Gatius , C , Grivé , M , Guzman , M C , Hernandez , R , Juscafresa , D , Leon , I , Macia , E , Mainou , A , Marco , E , Martinez , M , Martinez , E , Molinero , C , Moncosi , X , Lopez-Mompó , C , Naranjo , M A , Navarro , D , Ortola , M E , Pérez , M C , Perez , M M , Prat , M , Pujol , R , Pujol , J , Ribatallada , A , Sánchez , R , Sarra , N , Teixidor , A , Valen , E , Valencia , I , Van Esso , D , Vila , C , Zabala , E & Zurilla , E 2015 , ' Influenza vaccine effectiveness assessment through sentinel virological data in three post-pandemic seasons ' , Human Vaccines and Immunotherapeutics , vol. 11 , no. 1 , pp. 225-230 . https://doi.org/10.4161/hv.36155
NO Publisher Copyright: © 2015 Landes Bioscience.
DS TECNALIA Publications
RD 30 jul 2024