RT Journal Article T1 Burden of Disease (BoD) Assessment to Estimate Risk Factors Impact in a Real Nanomanufacturing Scenario A1 Koivisto, Antti Joonas A1 Altin, Marko A1 Furxhi, Irini A1 Eliat, Maxime A1 Trabucco, Sara A1 Blosi, Magda A1 Lopez de Ipiña, Jesús A1 Belosi, Franco A1 Costa, Anna AB An industrial nanocoating process air emissions impact on public health was quantified by using the burden of disease (BoD) concept. The health loss was calculated in Disability Adjusted Life Years (DALYs), which is an absolute metric that enables comparisons of the health impacts of different causes. Here, the health loss was compared with generally accepted risk levels for air pollution. Exposure response functions were not available for Ag nanoform. The health loss for TiO2 nanoform emissions were 0.0006 DALYs per 100,000 persons per year. Moreover, the exposure risk characterization was performed by comparing the ground level air concentrations with framework values. The exposure levels were ca. 3 and 18 times lower than the derived limit values of 0.1 μg-TiO2/m3 and 0.01 μg-Ag/m3 for the general population. The accumulations of TiO2 and Ag nanoforms on the soil top layer were estimated to be up to 85 μg-TiO2/kg and 1.4 μg-Ag/kg which was considered low as compared to measured elemental TiO2 and Ag concentrations. This assessment reveals that the spray coating process air emissions are adequately controlled. This study demonstrated how the BoD concept can be applied to quantify health impacts of nanoform outdoor air emissions from an industrial site. SN 2079-4991 YR 2022 FD 2022-11 LK https://hdl.handle.net/11556/3799 UL https://hdl.handle.net/11556/3799 LA eng NO Koivisto , A J , Altin , M , Furxhi , I , Eliat , M , Trabucco , S , Blosi , M , Lopez de Ipiña , J , Belosi , F & Costa , A 2022 , ' Burden of Disease (BoD) Assessment to Estimate Risk Factors Impact in a Real Nanomanufacturing Scenario ' , Nanomaterials , vol. 12 , no. 22 , 4089 . https://doi.org/10.3390/nano12224089 NO Publisher Copyright: © 2022 by the authors. NO This work was supported by EU-project “ASINA” (Anticipating Safety Issues at the Design Stage of NAno Product Development). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement Nº 862444. This paper reflects only the authors’ views and the Commission is not responsible for any use that may be made of the information it contains. DS TECNALIA Publications RD 26 jul 2024