RT Conference Proceedings
T1 Automatic pigmented lesion segmentation through a dermoscopy-guided OCT approach for early diagnosis
A1 López Sarachaga, Cristina
A1 Lage, Sergio
A1 Morales, Maria Celia
A1 Boyano, Mª Dolores
A1 Asumendi, Aintzane
A1 Garrote, Estibaliz
A1 Conde, Olga M.
A1 Boyano, Ma Dolores
AB Early diagnosis of pigmented lesions, specially melanoma, is an unmet clinical need that would help to improve patient prognosis. Apart from histopathological biopsy, the only gold standard non-invasive imaging technique during diagnosis is dermatoscopy (DD). Over the last years, new medical imaging techniques are being developed and Optical Coherence Tomography (OCT) has demonstrated to be very helpful on dermatology. OCT is non-invasive and provides in-depth structural microscopic information of the skin in real-time. In comparison with other novel techniques, as Reflectance Confocal Microscopy (RCM), the acquisition time is lower and the field-of-view higher. Hence, consolidated diagnosis techniques and novel imaging modalities can be combined to improve decision making during diagnosis and treatment. With actual methods, the delineation of lesion margins directly on OCT images during early stages of the disease is still really challenging and, at the same time, relevant from a prognosis perspective. This work proposes combining DD and OCT images to take advantage of their complementary information. The goal is to guide lesions delineation on OCT images considering the clinical features on DD images. The developed method applies image processing techniques to DD image to automatically segment the lesion; later, and after a calibration procedure, DD and OCT images become coregistered. In a final step the DD segmentation is transferred into the OCT image. Applying advanced image processing techniques and the proposed strategy of lesion delimitation, histopathological characteristics of the segmented lesion can be studied on OCT images afterwards. This proposal can lead to early, real-time and non-invasive diagnosis of pigmented lesions.
SN 1605-7422
YR 2019
FD 2019
LA eng
NO López Sarachaga , C , Lage , S , Morales , M C , Boyano , M D , Asumendi , A , Garrote , E , Conde , O M & Boyano , M D 2019 , ' Automatic pigmented lesion segmentation through a dermoscopy-guided OCT approach for early diagnosis ' , Progress in Biomedical Optics and Imaging - Proceedings of SPIE , vol. 10851 , 108510K . https://doi.org/10.1117/12.2508002
NO Publisher Copyright: © 2019 SPIE.
DS TECNALIA Publications
RD 3 jul 2024