%0 Journal Article %A Bilenberg, B. %A Hansen, M. %A Johansen, D. %A Ă–zkapici, V. %A Jeppesen, C. %A Szabo, P. %A Obieta, I. M. %A Arroyo, O. %A Tegenfeldt, J. O. %A Kristensen, A. %T Topas-based lab-on-a-chip microsystems fabricated by thermal nanoimprint lithography %D 2005 %@ 1071-1023 %U https://hdl.handle.net/11556/4243 %X We present a one-step technology for fabrication of Topas-based lab-on-a-chip (LOC) microsystems by the use of thermal nanoimprint lithography (NIL). The technology is demonstrated by the fabrication of two working devices: a particle separator and a LOC with integrated optics for absorbance measurements. These applications demonstrate the fabrication of millimeter to micrometer-sized structures in one lithographic step. The use of NIL makes the technology easily scalable into the nanometer regime by the use of a suitable lithographic technique in the fabrication of the stamp. Processing issues such as environmental stress cracking of the Topas and the requirements to anti-sticking layers on the stamp when imprinting into Topas are discussed. %~