TY - CHAP AU - Lombrana, J. I. AU - Mijangos, F. AU - Varona, F. AU - Villaran, M. C. PY - 1991 SN - 0444893520 SN - 9780444893529 UR - https://hdl.handle.net/11556/1935 AB - A simplified mathematical sublimation model is presented to describe the freeze-drying rate. Freeze-drying was simulated for two pharmaceuticals with very different properties. Different operational profiles were obtained for the heating and pressure... LA - eng PB - Amsterdam, The Netherlands, Elsevier Science Publishers TI - Near-optimum heating profiles in freeze-drying in accordance to the transport parameters and product nature TY - book part ER -