RT Journal Article T1 Integrated 3D Hydrogel Waveguide Out-Coupler by Step-and-Repeat Thermal Nanoimprint Lithography: A Promising Sensor Device for Water and pH: A promising sensor device for water and pH A1 Francone, Achille A1 Kehoe, Timothy A1 Obieta, Isabel A1 Saez-Martinez, Virginia A1 Bilbao, Leire A1 Khokhar, Ali Z. A1 Gadegaard, Nikolaj A1 Delgado Simao, Claudia A1 Kehagias, Nikolaos A1 Sotomayor Torres, Clivia M. AB Hydrogel materials offer many advantages for chemical and biological sensoring due to their response to a small change in their environment with a related change in volume. Several designs have been outlined in the literature in the specific field of hydrogel-based optical sensors, reporting a large number of steps for their fabrication. In this work we present a three-dimensional, hydrogel-based sensor the structure of which is fabricated in a single step using thermal nanoimprint lithography. The sensor is based on a waveguide with a grating readout section. A specific hydrogel formulation, based on a combination of PEGDMA (Poly(Ethylene Glycol DiMethAcrylate)), NIPAAm (N-IsoPropylAcrylAmide), and AA (Acrylic Acid), was developed. This stimulus-responsive hydrogel is sensitive to pH and to water. Moreover, the hydrogel has been modified to be suitable for fabrication by thermal nanoimprint lithography. Once stimulated, the hydrogel-based sensor changes its topography, which is characterised physically by AFM and SEM, and optically using a specific optical set-up. SN 1424-3210 YR 2018 FD 2018-10 LA eng NO Francone , A , Kehoe , T , Obieta , I , Saez-Martinez , V , Bilbao , L , Khokhar , A Z , Gadegaard , N , Delgado Simao , C , Kehagias , N & Sotomayor Torres , C M 2018 , ' Integrated 3D Hydrogel Waveguide Out-Coupler by Step-and-Repeat Thermal Nanoimprint Lithography: A Promising Sensor Device for Water and pH : A promising sensor device for water and pH ' , Sensors , vol. 18 , no. 10 , 3240 , pp. 3240 . https://doi.org/10.3390/s18103240 NO Publisher Copyright: © 2018 by the authors. Licensee MDPI, Basel, Switzerland. DS TECNALIA Publications RD 22 jul 2024