%0 Generic
%A Annaz, B.
%A Reid, B.
%A Olalde, B.
%A Jurado, M. J.
%A Alava, J. I.
%A McCaig, C. D.
%A Gibson, I. R.
%T Osteoblast response to single wall carbon nanotube-PLLA composites
%J 8th World Biomaterials Congress 2008
%D 2008
%U https://hdl.handle.net/11556/2524
%X This study showed that incorporation of single-walled carbon nanotubes (1wt%) in to PLLA polymer resulted in a large decrease in resistivity, but did not appear to affect the growth and viability of osteoblast-like cells. Also, incorporation of SWCNTs resulted in no significant difference in alkaline phosphatase activity, an important early-stage marker of osteogenic differentiation, of BMSC. These initial studies suggest that SWCNTs did not have a negative effect on cell behaviour, compared to results reported for MWCNT [2]; this could be related to the purity of CNTs used in the present study. Further, long term studies are required to determine if there is a toxic response to the SWCNTs as the PLLA degrades.
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