RT Journal Article T1 Human study of ion implantation as a surface treatment for dental implants A1 De Maeztu, M. A. A1 Braceras, I. A1 Álava, J. I. A1 Recio, C. A1 Piñera, M. A1 Gay-Escoda, C. AB This clinical study evaluated a new surface treatment of ion implantation with CO ions which has previously been subjected to extensive study in animal models. The aim of this work was to assess its effect in humans. Experimental mini-implants were used; half of their longitudinal surface was machined and the other half was treated with CO ion implantation. The study was conducted in healthy volunteer patients who required prosthetic treatment with dental implants, and in accordance with the corresponding ethics committees. Coinciding with the insertion of commercial implants for oral restoration, one or two mini-implants were placed in the upper maxillary tuberosity or in the retromolar trigone of the mandible. The mini-implants were removed with a trephine jointly with a small volume of surrounding bone after a 3-month period. Two evaluation methods were used and both showed a greater degree of bone integration in the mini-implant section that underwent CO ion implantation treatment in comparison with the non-treated surface: 62.9% vs. 57.9%, and 54.8% vs. 46.2%. In addition, no adverse reactions were observed in the surface treatment with CO ion implantation. These results confirm the positive benefits in humans, based on the findings obtained from previous animal experiments. SN 0901-5027 YR 2013 FD 2013-07 LK https://hdl.handle.net/11556/3504 UL https://hdl.handle.net/11556/3504 LA eng NO De Maeztu , M A , Braceras , I , Álava , J I , Recio , C , Piñera , M & Gay-Escoda , C 2013 , ' Human study of ion implantation as a surface treatment for dental implants ' , International Journal of Oral and Maxillofacial Surgery , vol. 42 , no. 7 , pp. 891-896 . https://doi.org/10.1016/j.ijom.2013.02.020 NO The study was partially funded by Fondo Tecnológico Sortek . DS TECNALIA Publications RD 26 jul 2024