RT Journal Article T1 Clinical, physical, physiological, and dietary patterns of obese and sedentary adults with primary hypertension characterized by sex and cardiorespiratory fitness: EXERDIET-HTA study A1 Gorostegi-Anduaga, Ilargi A1 Corres, Pablo A1 Jurio-Iriarte, Borja A1 Martínez-Aguirre, Aitor A1 Pérez-Asenjo, Javier A1 Aispuru, Gualberto R. A1 Arenaza, Lide A1 Romaratezabala, Estibaliz A1 Arratibel-Imaz, Iñaki A1 Mujika, Iñigo A1 Francisco-Terreros, Silvia A1 Maldonado-Martín, Sara AB The main purpose of this study was to determine some key physical, physiological, clinical, and nutritional markers of health status in obese and sedentary adults (54.0 ± 8.1 years, 141 men and 68 women) with primary hypertension (HTN) characterized by sex and cardiorespiratory fitness (CRF) level. The studied population showed a high cardiovascular risk (CVR) profile including metabolically abnormal obese, with poor CRF level (22.5 ± 5.6 mL·kg−1·min−1), exercise-induced HTN (Systolic Blood Pressure>210 mmHg in men and >190 mmHg in women at the end of the exercise test) and with non-healthy adherence to dietary pattern (Dietary Approaches to Stop Hypertension, 46.3%; Mediterranean Diet, 41.1%; and Healthy Diet Indicator, 37.1%). Women showed a better biochemical and dietary pattern profile than men (lower values, P < 0.05, in triglycerides, mean difference = 26.3; 95% CI = 0.9–51.7 mg/dL, aspartate transaminase, mean difference = 4.2; 95% CI = 0.3–8.0 U/L; alanine transaminase, mean difference = 8.2; 95% CI = 1.6–14.8 U/L; gamma-glutamyl transpeptidase, mean difference = 11.0; 95% CI = -1.1–23.2 U/L and higher values, P = 0.002, in high-density lipoprotein cholesterol, mean difference = 5.0, 95% CI = -13.3–3.3 mg/dL), but physical and peak exercise physiological characteristics were poorer. A higher CRF level might contribute to the attenuation of some CVR factors, such as high body mass index, non-dipping profile, and high hepatic fat. The results strongly suggest that targeting key behaviors such as improving nutritional quality and CRF via regular physical activity will contribute to improving the health with independent beneficial effects on CVR factors. SN 1064-1963 YR 2018 FD 2018-02-17 LK https://hdl.handle.net/11556/3506 UL https://hdl.handle.net/11556/3506 LA eng NO Gorostegi-Anduaga , I , Corres , P , Jurio-Iriarte , B , Martínez-Aguirre , A , Pérez-Asenjo , J , Aispuru , G R , Arenaza , L , Romaratezabala , E , Arratibel-Imaz , I , Mujika , I , Francisco-Terreros , S & Maldonado-Martín , S 2018 , ' Clinical, physical, physiological, and dietary patterns of obese and sedentary adults with primary hypertension characterized by sex and cardiorespiratory fitness : EXERDIET-HTA study ' , Clinical and Experimental Hypertension , vol. 40 , no. 2 , pp. 141-149 . https://doi.org/10.1080/10641963.2017.1346111 NO Publisher Copyright: © 2017 Taylor & Francis. NO The study was supported by the University of the Basque Country (GIU14/21 and EHU14/08). DS TECNALIA Publications RD 31 jul 2024