%0 Generic
%A de Jong, Bas
%A Belar, Oihana
%A Bereciartua, Arantza
%A Picon, Artzai
%A Muñoz, Elena
%A Sevilla, D.
%A Moscone, F.
%A Gandon, Fabienne
%A Tosseti, E.
%A García, S.
%A Riegman, Peter
%A Bilbao, Roberto
%T Services Associated to Digitalised Contents of Tissues in Biobanks Across Europe: A Proof of Concept – BIOPOOL
%D 2013
%U http://hdl.handle.net/11556/242
%X Background: Pathology departments and biobanks are increasingly usingDigital Pathology (DP) images for sharing of research results, ring trials,education, fast second-opinion diagnostics, pathology panels, digitalback-up of slides, image analysis algorithms, and etcetera. To fullyexploit the potential of DP, the BIOPOOL project develops software forextracting and gathering DP slides with well defined associated datafrom multiple biobanks and pathology archives to create pools ofimages, as biobanks networks, on which clinicians and researchers cansearch for reference, score for similarities with their own images usingan innovative Content Based Image Retrieval system, and perform indepthimage analyses. Methods: The BIOPOOL Proof-of-Concept (PoC)with minimal, critical functionality serves as the basis on which thesystem will be further developed. For this PoC we are studying existingDP image formats and systems that could be of use, designed both PoCand end-phase validation plans and end-phase functional requirements.Results: For the PoC, only colon DP slides with associated data (normaland high grade carcinoma), digitalised on Hamamatsu and Olympusscanners, are used. Pathologists have assigned morphological areas ofinterest for image searching development and creation of the basic DPpool,which were both validated. Functional requirements include auser-interface for searching on textual and morphology aspects, multiscannerformat support, storage capacity, computational power forsearch processing and IT equipment and support. Conclusions: The PoCmodel is a template for expanding the BIOPOOL system to fullfunctionality. After final validation BIOPOOL may then serve as a leadingexample for using the full potential of DP imaging.
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