In vitro evaluation of combined laser processing on Ti6Al4V discs: Macrostructuring and pulsed laser deposition

No Thumbnail Available
Identifiers
URI: https://hdl.handle.net/11556/3596
ISSN: 1013-9826
Publication date
2008
Authors
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Citations
Google Scholar
Export
Research Projects
Organizational Units
Journal Issue
Abstract
Human fetal osteoblast (hFOB) cell adhesion and cell proliferation studies have been performed on laser macrostructured titanium alloy substrates with and without pulsed laser deposited thin calcium phosphate coating. Coating was only 100 nm thick. The combined laser processing approach for modification of titanium alloy surfaces has yielded improved cell adhesion and proliferation of cells. Alkaline phosphatase activity was very significantly higher in the coated samples suggesting a intense stimuli of early osteoblast differentiation that should lead to improve bone growth on these surfaces.
Description
Keywords
Hydroxyapatite , In vitro tests , Macrostructure , Pulsed laser deposition , Ti6l4V , General Materials Science , Mechanics of Materials , Mechanical Engineering
Type
journal article
Citation
Paz , M D , Chiussi , S , González , P , Serra , J , León , B , Goikoetxea , L & Alava , J I 2008 , ' In vitro evaluation of combined laser processing on Ti6Al4V discs : Macrostructuring and pulsed laser deposition ' , Key Engineering Materials , vol. 361-363 I , pp. 625-628 .