Design and Fabrication of Printed Human Skin Model Equivalent Circuit: A Tool for Testing Biomedical Electrodes without Human Trials

Simple item page
dc.contributor.authorPeřinka, Nikola
dc.contributor.authorŠtrbac, Matija
dc.contributor.authorKostić, Milos
dc.contributor.authorMalešević, Jovana
dc.contributor.authorCastro, Nélson
dc.contributor.authorCorreia, Vítor
dc.contributor.authorLanceros-Méndez, Senentxu
dc.contributor.institutionSG
dc.date.issued2022-02
dc.descriptionPublisher Copyright: © 2021 Wiley-VCH GmbH
dc.description.abstractWithin the efforts of developing a new generation of biomedical electrodes with embedded switching logics, developing safe and simple procedures for testing these novel systems is tackled. The development and demonstration of an all-printed flexible testbed for automated validation and testing of multi pad systems is presented. The system is based on a Human model equivalent circuit (HMEC), which, when connected to the electrical stimulation system, mirrors the electrical behavior of biomedical electrodes and their specific interface material as if they are placed on a human subject. A simulation model of the electrical stimulation system components was developed based on the experimental data, in order to optimize printed electronic components’ characteristics and design. The testbed is composed of five layers of different conductive and dielectric materials screen-printed on a flexible poly(ethylene terephthalate) (PET) substrate. The system was prototyped with the characteristic values of the HMEC matching the average experimental data acquired from human subjects. Thus, it is demonstrated that an all printed flexible HMEC is a feasible approach to enabling the functional testing of transcutaneous electrical stimulation devices required for their fabrication, evaluation and optimization, reducing the need for tests on human subjects in the development phase of new systems.en
dc.description.sponsorshipThe authors acknowledge the receipt of funding from the European Union's Horizon 2020 Programme for Research, ICT‐02‐2018—Flexible and Wearable Electronics, Grant agreement no. 824339—WEARPLEX. The authors thank the FCT (Fundação para a Ciência e Tecnologia) for financial support under the framework of Strategic Funding grants UID/FIS/04650/2020. V.C. thanks FCT for the junior researcher contract (DL57/2016) and the R&D Units Project Scope: UIDB/00319/2020. Financial support from the Spanish State Research Agency (AEI) and the European Regional Development Fund (ERFD) through the project PID2019‐106099RB‐C43/AEI/10.13039/501100011033 and from the Basque Government Industry and Education Departments under the Elkartek, Hazitek, and PIBA (PIBA‐2018‐06) programs, respectively, is also acknowledged. The authors thank for the technical and human support provided by SGIker (UPV/EHU/ERDF). The authors acknowledge the receipt of funding from the European Union's Horizon 2020 Programme for Research, ICT-02-2018?Flexible and Wearable Electronics, Grant agreement no. 824339?WEARPLEX. The authors thank the FCT (Funda??o para a Ci?ncia e Tecnologia) for financial support under the framework of Strategic Funding grants UID/FIS/04650/2020. V.C. thanks FCT for the junior researcher contract (DL57/2016) and the R&D Units Project Scope: UIDB/00319/2020. Financial support from the Spanish State Research Agency (AEI) and the European Regional Development Fund (ERFD) through the project PID2019-106099RB-C43/AEI/10.13039/501100011033 and from the Basque Government Industry and Education Departments under the Elkartek, Hazitek, and PIBA (PIBA-2018-06) programs, respectively, is also acknowledged. The authors thank for the technical and human support provided by SGIker (UPV/EHU/ERDF).
dc.description.statusPeer reviewed
dc.format.extent1
dc.identifier.citationPeřinka , N , Štrbac , M , Kostić , M , Malešević , J , Castro , N , Correia , V & Lanceros-Méndez , S 2022 , ' Design and Fabrication of Printed Human Skin Model Equivalent Circuit : A Tool for Testing Biomedical Electrodes without Human Trials ' , Advanced Engineering Materials , vol. 24 , no. 2 , 2100684 , pp. 2100684 . https://doi.org/10.1002/adem.202100684
dc.identifier.doi10.1002/adem.202100684
dc.identifier.issn1438-1656
dc.identifier.otherresearchoutputwizard: 11556/1303
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85120969155&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofAdvanced Engineering Materials
dc.relation.projectIDBasque Government Industry and Education Departments, PIBA‐2018‐06
dc.relation.projectIDCi?ncia e Tecnologia
dc.relation.projectIDFundação para a Ciência e Tecnologia, UID/FIS/04650/2020-UIDB/00319/2020-DL57/2016
dc.relation.projectIDHorizon 2020 Framework Programme, H2020, 825339
dc.relation.projectIDEuropean Commission, EC, 824339
dc.relation.projectIDFundação para a Ciência e a Tecnologia, FCT
dc.relation.projectIDEuskal Herriko Unibertsitatea, EHU
dc.relation.projectIDUniversitat Politècnica de València, UPV
dc.relation.projectIDEuropean Regional Development Fund, ERDF, PID2019‐106099RB‐C43/AEI/10.13039/501100011033
dc.relation.projectIDAgencia Estatal de Investigación, AEI
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subject.keywordselectrode
dc.subject.keywordsequivalent circuit
dc.subject.keywordsprinting
dc.subject.keywordsskin model
dc.subject.keywordstestbed
dc.subject.keywordsElectrode
dc.subject.keywordsEquivalent circuit
dc.subject.keywordsPrinting
dc.subject.keywordsSkin model
dc.subject.keywordsTestbed
dc.subject.keywordsGeneral Materials Science
dc.subject.keywordsCondensed Matter Physics
dc.subject.keywordsFunding Info
dc.subject.keywordsBasque Government Industry and Education Departments PIBA‐2018‐06
dc.subject.keywordsBasque Government Industry and Education Departments PIBA‐2018‐06
dc.titleDesign and Fabrication of Printed Human Skin Model Equivalent Circuit: A Tool for Testing Biomedical Electrodes without Human Trialsen
dc.typejournal article
Files