Browsing by Keyword "Probiotic"
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Item Characterisation of the probiotic potential of Lactiplantibacillus plantarum K16 and its ability to produce the postbiotic metabolite γ-aminobutyric acid(2022-10) Diez-Gutiérrez, Lucía; San Vicente, Leire; Sáenz, Jessica; Barron, Luis Javier R.; Chávarri, María; Tecnalia Research & Innovation; Alimentación SostenibleLactiplantibacillus plantarum has been widely studied due to its beneficial effects on health such as protect against pathogens, enhance the immune system, or produce metabolites like γ-aminobutyric acid (GABA). The objective of this study was the evaluation of the GABA-producer L. plantarum K16 isolated from kimchi. The safety and probiotic characterisation of this strain was performed by analysing carbohydrates fermentation, enzymatic activity, antibiotics susceptibility, and haemolytic and antimicrobial activity. Likewise, GABA production was optimised following a one-factor-at-a-time procedure by changing relevant fermentation parameters like incubation temperature, yeast extract concentration and fermentation time. The results indicated that L. plantarum K16 has the potential to stimulate the digestion and absorption of several nutrients and it could have an inhibitory effect against pathogenic bacteria. The best results for GABA production by this strain was around 1000 mg/L, using 12 g/L of yeast extract, 34 °C of incubation temperature and 96 h of fermentation time.Item Gamma-aminobutyric acid and probiotics: Multiple health benefits and their future in the global functional food and nutraceuticals market: Multiple health benefits and their future in the global functional food and nutraceuticals market(2020-01) Diez-Gutiérrez, Lucía; San Vicente, Leire; R. Barrón, Luis Javier; Villarán, María del Carmen; Chávarri, María; Tecnalia Research & Innovation; Alimentación SostenibleProbiotics have attracted growing interest in recent decades due to their multiple health benefits. The synergistic relationship between probiotics and prebiotics can enhance the production of metabolites called postbiotics, which are gaining increasing importance because of their beneficial functions in the gastrointestinal tract and their influence on different organs and tissues. Notable among the postbiotics is gamma-aminobutyric acid, which plays an essential role in the prevention of neural disease, type 1 diabetes, cancer, immunological disorders and asthma. Generally, gamma-aminobutyric acid is produced by lactic acid bacteria, which under certain conditions can produce a high amount of this amino acid. The food industry has leveraged this capacity to develop functional foods enriched with gamma-aminobutyric acid.Item The role of probiotics in nutritional health: probiotics as nutribiotics: probiotics as nutribiotics(Academic Press; Elsevier Inc., 2022-01-01) Chávarri, María; Diez-Gutiérrez, Lucía; Marañón, Izaskun; del Carmen Villarán, María; Barrón, Luis Javier R.; Alimentación Sostenible; Tecnalia Research & InnovationThe gut microbiota has gained importance through the years due to its significant influences on the maintenance of human health. A wide variety of microorganisms shape this gut microbiota, which preserves health with the modulation of the immune system, enhancement of the nutrients absorption, or the protection against pathogens’ colonization. The disruption of this microenvironment triggers the development of health problems leading to several diseases, such as nutritional health problems. The preservation and restoration of this microbiota is a key factor to maintain the natural body homeostasis. According to nutritional health problems, a long list of probiotics and postmiotic has been classified as nutribiotics due to their potential to improve the nutritional status of people. Likewise, nutribiotics should be properly protected and supply using an adequate encapsulation technique. Furthermore, the rising interest in this kind of products is producing the expansion of the current market and opening multiple business opportunities.