Positive Connectivity Predicts the Dynamic Intrinsic Topology of the Human Brain Network
StatisticsView Usage Statistics
Full recordShow full item record
Author/sQian, Jingyu; Diez, Ibai; Ortiz-Terán, Laura; Bonadio, Christian; Liddell, Thomas; [et al.]
Functional connectivity MRI
Stepwise functional connectivity
Functional connectivity MRI (fcMRI) has become instrumental in facilitating research of human brain network organization in terms of coincident interactions between positive and negative synchronizations of large-scale neuronal systems. Although there is a common agreement concerning the interpretation of positive couplings between brain areas, a major debate has been made in disentangling the nature of negative connectivity patterns in terms of its emergence in several methodological approaches and its significance/meaning in specific neuropsychiatric diseases. It is still not clear what information the functional negative correlations or connectivity provides or how they relate to the positive connectivity. Through implementing stepwise functional connectivity (SFC) analysis and studying the causality of functional topological patterns, this study aims to shed light on the relationship between positive and negative connectivity in the human brain functional connectome. We found that ...