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dc.contributor.authorAntolín-Urbaneja, Juan Carlos
dc.contributor.authorEguizabal, I.
dc.contributor.authorBriz, N.
dc.contributor.authorDominguez, A.
dc.contributor.authorEstensoro, Patxi
dc.contributor.authorSecchi, A.
dc.contributor.authorVarriale, A.
dc.contributor.authorDi Giovanni, S.
dc.contributor.authorD´Auria, S.
dc.date.accessioned2016-02-23T16:14:39Z
dc.date.available2016-02-23T16:14:39Z
dc.date.issued2013
dc.identifier.citationOPTICAL SENSORS 2013, Proceedings of SPIE, 8774, UNSP 87741Jen
dc.identifier.isbn978-0-8194-9576-1en
dc.identifier.urihttp://hdl.handle.net/11556/119
dc.description.abstractSeveral techniques for detecting chemical drug precursors have been developed in the last decade. Most of them are able to identify molecules at very low concentration under lab conditions. Other commercial devices are able to detect a fixed number and type of target substances based on a single detection technique providing an absence of flexibility with respect to target compounds. The construction of compact and easy to use detection systems providing screening for a large number of compounds being able to discriminate them with low false alarm rate and high probability of detection is still an open concern. Under CUSTOM project, funded by the European Commission within the FP7, a stand-alone portable sensing device based on multiple techniques is being developed. One of these techniques is based on the LED induced fluorescence polarization to detect Ephedrine and Benzyl Methyl Keton (BMK) as a first approach. This technique is highly selective with respect to the target compounds due to the generation of properly engineered fluorescent proteins which are able to bind the target analytes, as it happens in an “immune-type reaction”. This paper deals with the advances in the design, construction and validation of the LED induced fluorescence sensor to detect BMK analytes. This sensor includes an analysis module based on high performance LED and PMT detector, a fluidic system to dose suitable quantities of reagents and some printed circuit boards, all of them fixed in a small structure (167mm x 193mm x 228mm) with the capability of working as a stand-alone application.en
dc.description.sponsorshipEuropean Commission´s FP7en
dc.language.isoengen
dc.publisherSPIE-INT SOC OPTICAL ENGINEERING, 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USAen
dc.titleCompact and cost effective instrument for detecting drug precursors in different environments based on fluorescence polarizationen
dc.typeconferenceObjecten
dc.identifier.doi10.1117/12.2017257
dc.isiYesen
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/FP7/242387/EU/Drugs and Precursor Sensing by Complementing Low Cost Multiple Techniques/CUSTOMen
dc.rights.accessRightsembargoedAccessen
dc.subject.keywordsDrug precursorsen
dc.subject.keywordsFluorescence proteinsen
dc.subject.keywordsFluorescence polarizationen
dc.subject.keywordsBMKen
dc.subject.keywordsBenzyl Methyl Ketonen
dc.subject.keywordsEphedrineen
dc.subject.keywordsLED induced fluorescence sensoren


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