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dc.contributor.authorLópez De Ipiña, Jesús M.
dc.contributor.authorVaquero, Celina
dc.contributor.authorEgizabal, Ainhoa
dc.contributor.authorPatelli, Alessandro
dc.contributor.authorMoroni, Lorenzo
dc.date.accessioned2021-07-12T09:43:22Z
dc.date.available2021-07-12T09:43:22Z
dc.date.issued2021-06
dc.identifier.citationLópez De Ipiña, Jesús M., Celina Vaquero, Ainhoa Egizabal, Alessandro Patelli, and Lorenzo Moroni. “Safe-by-Design Strategies Applied to Scaffold Hybrid Manufacturing.” Journal of Physics: Conference Series 1953, no. 1 (June 1, 2021): 012009. doi:10.1088/1742-6596/1953/1/012009.en
dc.identifier.issn1742-6588en
dc.identifier.urihttp://hdl.handle.net/11556/1167
dc.description.abstractThe EU-project FAST (GA 685825) has developed a 3D printer machine prototype for the manufacture of bone implants (scaffolds), by merging masterbatches of biodegradable polymer poly(ethylene oxide)terephthalate/poly(butylene terephthalate) [PEOT/PBT] doped with nanofillers [reduced graphene oxide (rGO), hydroxyapatite (HA) and magnesium aluminium hydroxide ciprofloxacin hydrotalcite (LDH-CFX)], and atmospheric plasma technology. This paper focus on the safe design strategies identified by FAST to address the risk to health resulting from the potential airborne emission of nano-objects and their aggregates and agglomerates (NOAAs) by the 3D printer prototype, which might result in occupational exposures by inhalation. The work also includes measurements of airborne emissions and occupational exposures carried out during the verification stage of the prototype design. Nanofillers particles (rGO, n-HA, LDH-CFX) were not observed, neither at source nor in the working area, suggesting no release of free nanofillers to the air one they have been embedded in the polymer masterbatch. Additionally, the exposure in the workplace was far below the selected Occupational Exposure Levels (OELs), for total particle number concentration (PNC), dust, elemental carbon (EC) and volatile organic compounds (VOCs). The results showed that, when working with the current prototype in normal operation (for its intended use) and with controls enabled [enclosure with the doors closed and Local Exhaust Ventilation (LEV) activated], the emission from the machine and the worker's exposure to NOAAs are well controlled.en
dc.description.sponsorshipThe project FAST received funding from the European Union’s Horizon 2020 research and innovation programme, under grant agreement Nº 685825. This paper reflects only the authors’ views, and the Commission is not responsible for any use that may be made of the information contained therein.en
dc.language.isoengen
dc.publisherIOP Publishing Ltden
dc.titleSafe-by-design strategies applied to scaffold hybrid manufacturingen
dc.typeconferenceObjecten
dc.identifier.doi10.1088/1742-6596/1953/1/012009en
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/685825/EU/Functionally graded Additive Manufacturing scaffolds by hybrid manufacturing/FASTen
dc.rights.accessRightsopenAccessen
dc.subject.keywordsHealth risksen
dc.subject.keywordsPrinting pressesen
dc.subject.keywordsSafety engineeringen
dc.subject.keywordsVolatile organic compoundsen
dc.subject.keywordsVentilation exhaustsen
dc.subject.keywords3D printersen
dc.identifier.essn1742-6596en
dc.issue.number1en
dc.journal.titleJournal of Physics: Conference Seriesen
dc.page.initial012009en
dc.volume.number1953en
dc.conference.title7th Nanosafe International Conference on Health and Safety Issues Related to Nanomaterials for a Socially Responsible Approach, NANOSAFE 2020, 16 November 2020 - 20 November 2020en


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