dc.contributor.author | Lohse, Mirko | |
dc.contributor.author | Thesen, Manuel W. | |
dc.contributor.author | Haase, Anja | |
dc.contributor.author | Smolka, Martin | |
dc.contributor.author | Iceta, Nerea Briz | |
dc.contributor.author | Ayerdi Izquierdo, Ana | |
dc.contributor.author | Ramos, Isbaal | |
dc.contributor.author | Salado, Clarisa | |
dc.contributor.author | Schleunitz, Arne | |
dc.date.accessioned | 2021-04-13T10:43:14Z | |
dc.date.available | 2021-04-13T10:43:14Z | |
dc.date.issued | 2021-04-01 | |
dc.identifier.citation | Lohse, Mirko, Manuel W. Thesen, Anja Haase, Martin Smolka, Nerea Briz Iceta, Ana Ayerdi Izquierdo, Isbaal Ramos, Clarisa Salado, and Arne Schleunitz. “Novel Concept of Micro Patterned Micro Titer Plates Fabricated via UV-NIL for Automated Neuronal Cell Assay Read-Out.” Nanomaterials 11, no. 4 (April 1, 2021): 902. doi:10.3390/nano11040902. | en |
dc.identifier.uri | http://hdl.handle.net/11556/1108 | |
dc.description.abstract | The UV-nanoimprint lithography(UV-NIL) fabrication of a novel network of micron-sized
channels, forming an open channel microfluidic system is described. Details about the complete
manufacturing process, from mastering to fabrication in small batches and in high throughput with
up to 1200 micro titer plates per hour is presented. Deep insight into the evaluation of a suitable
UV-curable material, mr-UVCur26SF is given, presenting cytotoxic evaluation, cell compatibility
tests and finally a neuronal assay. The results indicate how the given pattern, in combination with
the resist, paves the way to faster, cheaper, and more reliable drug screening. | en |
dc.description.sponsorship | This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement NO. 646260. The research was also partially supported by NextGenMicrofluidics project under HORIZON2020 with grant agreement no 862092. | en |
dc.language.iso | eng | en |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | en |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.title | Novel Concept of Micro Patterned Micro Titer Plates Fabricated via UV-NIL for Automated Neuronal Cell Assay Read-Out | en |
dc.type | article | en |
dc.identifier.doi | 10.3390/nano11040902 | en |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/646260/EU/Large scale micro-and nanofabrication technologies for bioanalytical devices based on R2R imprinting/R2R Biofluidics | en |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/862092/EU/Next generation test bed for upscaling of microfluidic devices based on nano-enabled surfaces and membranes/NextGenMicrofluidics | en |
dc.rights.accessRights | openAccess | en |
dc.subject.keywords | Nanoimprint lithography | en |
dc.subject.keywords | R2R UV-NIL | en |
dc.subject.keywords | Neuronal cell assay | en |
dc.identifier.essn | 2079-4991 | en |
dc.issue.number | 4 | en |
dc.journal.title | Nanomaterials | en |
dc.page.initial | 902 | en |
dc.volume.number | 11 | en |