%0 Journal Article 
%A Spüler, Martin
%A López-Larraz, Eduardo
%A Ramos-Murguialday, Ander
%T On the design of EEG-based movement decoders for completely paralyzed stroke patients
%D 2018
* NLM (Medline)
%X Background: Brain machine interface (BMI) technology has demonstrated its efficacy for rehabilitation of paralyzed
chronic stroke patients. The critical component in BMI-training consists of the associative connection (contingency)
between the intention and the feedback provided. However, the relationship between the BMI design and its
performance in stroke patients is still an open question.
Methods: In this study we compare different methodologies to design a BMI for rehabilitation and evaluate their
effects on movement intention decoding performance. We analyze the data of 37 chronic stroke patients who
underwent 4 weeks of BMI intervention with different types of association between their brain activity and the
proprioceptive feedback. We simulate the pseudo-online performance that a BMI would have under different
conditions, varying: (1) the cortical source of activity (i.e., ipsilesional, contralesional, bihemispheric), (2) the type of
spatial filter applied, (3) the EEG frequency band, (4) the type of classifier; and also evaluated the use of residual
EMG activity to decode the movement intentions.
Results: We observed a significant influence of the different BMI designs on the obtained performances. Our results
revealed that using bihemispheric beta activity with a common average reference and an adaptive support vector
machine led to the best classification results. Furthermore, the decoding results based on brain activity were
significantly higher than those based on muscle activity.
Conclusions: This paper underscores the relevance of the different parameters used to decode movement, using
EEG in severely paralyzed stroke patients. We demonstrated significant differences in performance for the different
designs, which supports further research that should elucidate if those approaches leading to higher accuracies also
induce higher motor recovery in paralyzed stroke patients.
%@ 1743-0003
%K Neuroprostheses
%K Brain machine interface (BMI)
%K Rehabilitation robotics
%K Proprioceptive feedback
%K Motor rehabilitation
%K Stroke
%K Neurotechnology
doi 10.1186/s12984-018-0438-z
%U http://hdl.handle.net/11556/662
%~ GOEDOC, SUB GOETTINGEN